Anti-Lysozyme

Anti-Lysozyme is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against lysozyme in human serum or plasma.
This test for antineutrophil cytoplasmic antibodies (ANCA) against lysozyme allows cases involving a positive immunofluorescence test for ANCA, but negative direct tests for proteinase 3 (PR3) and myeloperoxidase (MPO) antibodies to be cleared up quickly and reliably.

Lysozyme is a glucosidase localised in the specific granules of neutrophils. In indirect immunofluorescence tests, lysozyme antibodies give a typical pANCA pattern. Their detection indicates rheumatoid vasculitis or Sjögren’s syndrome; they may also occur in cases of SLE and ulcerative colitis.

Specifications

Product Number ORG 226
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 100 U/ml
Cut-off10 U/ml
Coating lysozyme (human)

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

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